Millennium Begins Phase II RA Trial

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By: Tim Wright

Editor-in-Chief, Contract Pharma

Millennium Pharmaceuticals, Inc. initiated a randomized, double-blind, placebo-controlled Phase II study of MLN3897 in patients with rheumatoid arthritis (RA). MLN3897, an oral, small molecule designed to block CCR1, is a chemokine receptor believed to play a role in inflammatory disorders including RA. The study will assess the efficacy, safety and tolerability of MLN3897 in combination with methotrexate (MTX), a standard therapy for RA. As many as 186 patients with RA that have been taki...

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